SS-31

What is SS-31?

SS-31 (Szeto-Schiller peptide 31) is a synthetic tetrapeptide (4 amino acids; MW ≈ 638.8 Da; alternating aromatic and basic residues) developed through academic research at Cornell University. It belongs to a class of mitochondria-targeted peptides studied in cellular bioenergetics research. It is intended strictly for laboratory and research purposes.

Molecular & Structural Profile

SS-31 features an alternating aromatic-basic amino acid structural motif that provides characterized interactions with mitochondrial membrane structures in cellular research models. This structural property distinguishes it from other small peptides and is the basis for its application in mitochondrial bioenergetics research.

Areas of Active Scientific Investigation

Mitochondrial Bioenergetics Research: Studies examining cardiolipin interactions and electron transport chain function in cellular models.

Oxidative Stress Research: Investigations into reactive oxygen species (ROS) pathway dynamics in cellular systems.

Membrane Interaction Studies: Biophysical characterization of peptide-lipid bilayer interactions.

Comparative Peptide Studies: Research examining SS-31 alongside related mitochondria-targeted compounds.

Regulatory & Research Context

SS-31 is sold strictly for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or application of any kind. It is not approved by the FDA to diagnose, treat, cure, or prevent any disease or condition. Not for use in any living organism.

Scientific References

• Zhao K, Szeto HH, et al. Journal of Biological Chemistry. 2004.
• Birk AV, et al. Journal of the American Society of Nephrology. 2013.
• PubMed: PMC3601019