Selank

Product Description

What is Selank?

Selank is a synthetic heptapeptide (7 amino acids; MW ≈ 863.0 Da) developed through academic research at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is structurally derived from the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension sequence that provides enhanced resistance to enzymatic degradation compared to the parent molecule. It is intended strictly for laboratory and research purposes.

Molecular & Structural Profile

Selank's three-amino-acid C-terminal extension (Pro-Gly-Pro) — shared with the related compound Semax — significantly increases peptide stability against protease activity in laboratory research environments relative to native tuftsin. The molecule is studied in the context of neuropeptide pharmacology and GABAergic signaling pathway research in preclinical cellular models. No canonical single receptor has been definitively established; research continues across multiple receptor pathway candidates.

Structural Features

Amino acid count: 7 residues (heptapeptide)

Molecular weight: ~863.0 Da

Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro

Structural class: Linear tuftsin-derived neuropeptide analog

C-terminal modification: Pro-Gly-Pro extension (protease stabilization)

Parent peptide: Tuftsin (endogenous tetrapeptide)

Areas of Active Scientific Investigation

Neuropeptide Receptor Research: Investigations into receptor binding candidates and signaling pathway interactions in cellular models, including GABAergic and neuropeptide receptor systems.

Comparative Pharmacology: Studies examining Selank alongside tuftsin and related structural analogs in receptor binding assays.

Structural Stability Research: Investigations into Pro-Gly-Pro extension-mediated protease resistance relative to the native tuftsin tetrapeptide.

Molecular Biology Research: Academic studies examining gene expression pathway dynamics associated with neuropeptide receptor signaling in in vitro models.

Regulatory & Research Context

Selank is sold strictly for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or application of any kind. It is not approved by the FDA to diagnose, treat, cure, or prevent any disease or condition. Not for use in any living organism.