OP-PT141

Compound Identity

OP-PT-141 is a synthetic cyclic heptapeptide (7 amino acids; MW ≈ 1,025.2 Da) derived through academic research into the melanocortin receptor system. It is structurally related to alpha-melanocyte-stimulating hormone (α-MSH) with modifications that alter its receptor selectivity profile toward central melanocortin pathways.

Receptor Selectivity Profile

MC4R (Melanocortin 4 Receptor) — preferential binding affinity

MC3R (Melanocortin 3 Receptor) — secondary affinity

MC1R, MC5R — lower relative binding affinity in comparative studies

Structural Features

Amino acid count: 7 residues (cyclic heptapeptide)

Molecular weight: ~1,025.2 Da

Structural class: Cyclic melanocortin analog

Primary selectivity: Central melanocortin pathway (MC4R)

Areas of Active Scientific Investigation

CNS Receptor Research: Studies examining MC4R-mediated signaling in central nervous system cellular models.

Receptor Selectivity Studies: Academic investigations of binding affinity profiles across MC receptor subtypes.

Comparative Pharmacology: Research comparing OP-PT-141 with related melanocortin analogs.

Structure-Activity Relationship Studies: Research into the molecular determinants of MC4R selectivity.

Regulatory & Research Context

OP-PT-141 is sold strictly for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or application of any kind. It is not approved by the FDA to diagnose, treat, cure, or prevent any disease or condition. Not for use in any living organism.

Scientific References

• Molinoff PB, et al. Annals of the New York Academy of Sciences. 2003.
• PubMed: PMC3614010 | PMC6469411