Compound Identity
DSIP is a naturally occurring nonapeptide (9 amino acids; MW ≈ 848.9 Da; sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first isolated from rabbit cerebral venous blood in the 1970s. It is classified as a neuropeptide and is characterized in scientific literature for its hydrophilic and physicochemical properties as studied in neuropeptide transport research models.
Receptor Selectivity Profile
The molecular targets of DSIP remain incompletely characterized in the scientific literature. No single canonical receptor has been definitively established. Research continues into the peptide's receptor binding profile, with investigations across neuroendocrine and hypothalamic-pituitary axis signaling pathways in preclinical models.
Structural Features
Amino acid count: 9 residues (nonapeptide)
Molecular weight: ~848.9 Da
Structural class: Linear hydrophilic neuropeptide
BBB permeability: Documented in preclinical research models
Receptor characterization: Incompletely defined
Areas of Active Scientific Investigation
Neuroendocrine Research: Studies examining HPA axis modulation in preclinical models.
Neuropeptide Receptor Research: Ongoing investigation of DSIP molecular targets and binding partners.
Comparative Neuropeptide Studies: Research examining DSIP alongside other endogenous neuropeptides.
Neurophysiology Research: Studies examining slow-wave EEG activity parameters in animal models.
Regulatory & Research Context
DSIP is sold strictly for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or application of any kind. It is not approved by the FDA to diagnose, treat, cure, or prevent any disease or condition. Not for use in any living organism.
Scientific References
- Schoenenberger GA, Monnier M. Proceedings of the National Academy of Sciences. 1977.
- Graf MV, Kastin AJ. Neuroscience & Biobehavioral Reviews. 1986.
- PubMed: PMC3614010
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